Dealing With Clomid Side Effects

Sick young woman lying in the bed covered with blanket. Ill woman lying in bed with high temperature.

Clomid is often one of the first fertility medications prescribed to women for infertility treatments. This fertility drug can help induce ovulation or stimulate extra follicles and eggs, but it can have a few side effects.

Our guide will help you understand what things to do or avoid while taking Clomid.

What is Clomid?

Clomid or clomiphene citrate is a common fertility drug taken orally at the beginning of your menstrual cycle. It works as an “anti-estrogen” and causes the brain to think estrogen levels are low. The body accommodates by releasing more follicle-stimulating hormone (FSH), which stimulates mature follicles.

Clomid is often a good choice for women who don’t ovulate on their own or who need extra follicles and eggs to increase the chance of pregnancy.

Common Clomid Side Effects

Since Clomid works by blocking estrogen receptors, many Clomid side effects relate to its anti-estrogenic properties. Common Clomid side effects include:

  • Hot flashes
  • Headaches
  • Bloating
  • Mood swings
  • Breast tenderness

Some women experience a thin uterine lining during Clomid cycles and less cervical mucus. While less mucus can lower overall fertility, infertility treatments like artificial insemination and IUI don’t depend on this factor.

Less Common Clomid Side Effects

Most women have mild to no symptoms when taking Clomid. But some women experience less common side effects from Clomid.

Rare but severe Clomid side effects include blurred vision, flashes or spots, or intense nausea. These should always be reported to your doctor immediately.

There’s also an increased chance of having twins or multiples when taking Clomid. One study found that about 12% of pregnancies using Clomid were twin pregnancies, and just over 1% were triplets or quadruplets.

Things to Do (or Avoid) While Taking Clomid

To make the Clomid side effects more manageable, try these tips during your treatment cycle:

  • Wear light, loose-fitting clothing in case of a hot flash or night sweats. This can also help with bloating or abdominal discomfort.
  • Invest in supportive bras and limit high-intensity activities to lessen breast tenderness.
  • Prepare healthy snacks to help curb excess weight gain, an infrequent but possible side effect of Clomid.
  • Avoid large amounts of processed foods, sugars, and caffeine that can contribute to headaches and dizziness.
  • Put less pressure on your relationship with your partner. Talk about your emotional and physical needs before treatment begins and throughout the process.
  • Drink plenty of water to stay hydrated and combat bloating.
  • Practice self-care strategies that work for you to cope with mood swings and emotional sensitivity.
  • Try taking Clomid in the evening to sleep through side effects like nausea and headaches.

Support for Your Fertility Needs

As infertility medication experts, Mandell’s Clinical Pharmacy can help you understand what things to do or avoid while taking Clomid or any other fertility drug. View our Clomid frequently asked questions to learn even more. And, of course, if you have questions, our team is here to answer them.