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Leuprolide Trigger Injection

Mandell’s Clinical Pharmacy can custom compound Leuprolide trigger injections in a pre-filled syringe, with the exact dose requested by the physician.   Since it comes in a pre-filled syringe, no mixing or drawing up of medication is required.   Please do not confuse Leuprolide trigger with Leuprolide 2 Week Kit.  While they are made of the same medication, their respective uses are substantially different.  Please follow the specific instructions from your physician or nurse when administering this medication, as treatment approach can vary between IVF centers.

Common Side Effects/Comments

Common side effects include local discomfort, bruising and soreness at the injection site; ovarian hyperstimulation syndrome (OHSS) (excessive fluid retention and severe abdominal discomfort), vaginal bleeding, pelvic pain, breast tenderness, hot flashes, vaginal dryness, constipation, headache, weakness, and dizziness. There is potential for serious pulmonary conditions and thromboembolic events (difficulty breathing or chest tightness).

Contact the Physician Immediately

If the patient experiences an allergic reaction (difficulty breathing, closing of the throat, swelling of the lips, tongue or face, or hives); difficulty urinating, bone pain, numbness, tingling or weakness in the legs or arms. If the patient experiences symptoms of ovarian hyperstimulation syndrome (OHSS) (excessive fluid retention and severe abdominal discomfort) or symptoms of pulmonary conditions and thromboembolic events (difficulty breathing or chest tightness).

Missed Dose

It is crucial that this dose be given EXACTLY at the date and time instructed by your physician. If you miss your scheduled dose you must immediately contact your physician for instructions.